Categories of Psychedelic Drugs

Psychedelics are typically grouped based on their chemical structure and the way they interact with the brain.

Lysergamides

Compounds related to lysergic acid (ergoline scaffold).

  • LSD - Lysergic acid diethylamide, a classical psychedelic known for its powerful psychedelic effects.

Tryptamines

Indole-based compounds structurally similar to serotonin.

  • Psilocybin - Psilocybin is a naturally occurring psychedelic compound found in certain species of mushrooms, commonly referred to as 'magic mushrooms.' It has been used for centuries in various cultures for spiritual and healing purposes. Psilocybin is known for its ability to induce altered states of consciousness, including visual and auditory hallucinations, changes in perception of time and space, and profound emotional experiences. Recent research has explored its potential therapeutic applications in treating conditions such as depression, anxiety, PTSD, and addiction.
  • DMT - N,N-Dimethyltryptamine (DMT) is a powerful psychedelic compound found in various plants and animals. It is known for its intense and short-lived hallucinogenic effects, often described as a 'breakthrough' experience. DMT is typically consumed by smoking, vaporizing, or as part of traditional ayahuasca brews.

Phenethylamines

Phenethylamine scaffold; includes many psychedelics and entactogens.

  • MDMA - MDMA (3,4-methylenedioxymethamphetamine) is a synthetic drug known for its entactogenic effects, often used recreationally and in therapeutic settings. It enhances emotional connection, empathy, and sensory perception. Commonly referred to as 'ecstasy' or 'molly,' MDMA is typically consumed orally in pill or capsule form. Users should be aware of potential risks, including dehydration, hyperthermia, and serotonin syndrome, especially when combined with other substances.
  • MDA - MDA (3,4-Methylenedioxyamphetamine) is a synthetic empathogen-entactogen and psychedelic drug known for its stimulating effects, mood enhancement, and increased feelings of empathy and sociability. Similar to MDMA but often described as more hallucinogenic
  • 2C-B - 2C-B (4-Bromo-2,5-dimethoxyphenethylamine) is a synthetic psychedelic substance belonging to the 2C family of phenethylamines. It was first synthesized by Alexander Shulgin in the 1970s and is known for its unique combination of visual and tactile effects, often described as a blend of LSD and MDMA. 2C-B is typically consumed orally in tablet or capsule form, with effects lasting around 4 to 8 hours. Users report enhanced sensory perception, vivid visual hallucinations, and feelings of euphoria. However, it can also cause anxiety, nausea, and increased heart rate in some individuals. Due to its potent effects, 2C-B should be approached with caution and used responsibly.

Dissociatives

Typically NMDA antagonists producing dissociation and analgesia.

  • Ketamine - Ketamine is a dissociative anesthetic used medically for anesthesia and pain management, as well as recreationally for its dissociative and hallucinogenic effects.

Cannabinoids

Compounds acting on the endocannabinoid system (CB1/CB2).

  • Cannabis - Cannabis, commonly known as marijuana, is a psychoactive drug from the Cannabis plant used for medical or recreational purposes. The main psychoactive component is tetrahydrocannabinol (THC).